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品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Serum Polyclonal Antibody 描述 产品目录编号 07-002 品牌系列 Upstate
商名 - Upstate
描述 Anti-p67-phox Antibody 产品信息 格式 Serum 演示 rabbit antiserum containing 0.05% azide 应用 应用 This Anti-p67-phox Antibody is validated for use in IP, WB, IC for the detection of p67-phox. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 GST fusion protein corresponding to full-length human p67-phox. 宿主 Rabbit 特异性 p67-phox 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000433
Entrez基因汇总 This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease. 基因符号 - P67-PHOX
- NCF2
- NCF-2
- NOXA2
- p67phox
- p67-phox
纯化方法 Antiserum UniProt编号 - P19878
UniProt汇总 FUNCTION: SwissProt: P19878 # NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
SIZE: 526 amino acids; 59762 Da
SUBUNIT: Interacts with SYTL1 and RAC1. May interact with NOXO1.
SUBCELLULAR LOCATION: Cytoplasm.
DISEASE: SwissProt: P19878 # Defects in NCF2 are a cause of autosomal recessive chronic granulomatous disease (AR-CGD) [MIM:233710]; also known as autosomal cytochrome-b-positive chronic granulomatous disease. It causes recurrent infection by catalase-positive organisms.
SIMILARITY: SwissProt: P19878 ## Contains 1 OPR domain. & Contains 2 SH3 domains. & Contains 3 TPR repeats.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from HL-60 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µL
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