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品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-170 品牌系列 Upstate
商名 - Upstate
描述 Anti-Na+/K+ ATPase β-1 Antibody 产品信息 格式 Purified 演示 whole antiserum containing 0.05% sodium azide 应用 应用 Anti-Na+/K+ ATPase β-1 Antibody is an antibody against Na+/K+ ATPase β-1 for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Fusion protein corresponding to amino acids 152-340 of the beta 1 subunit 宿主 Rabbit 特异性 Na+/K+ ATPase β-1 同种型 IgG 品种反应性 Rat Species Reactivity Note Does not work in mouse. 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001677
Entrez基因汇总 The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified. 基因符号 - ATP1B
- ATP1B1
- MGC1798
- adenosinetriphosphatase
纯化方法 Antiserum UniProt编号 - P05026
UniProt汇总 FUNCTION: SwissProt: P05026 # This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
SIZE: 303 amino acids; 35061 Da
SUBUNIT: Composed of three subunits: alpha (catalytic), beta and gamma. Interacts with NKAIN1, NKAIN2 and NKAIN4 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
TISSUE SPECIFICITY: Found in most tissues.
SIMILARITY: SwissProt: P05026 ## Belongs to the X(+)/potassium ATPases subunit beta family.产品使用声明 质量保证 routinely evaluated by immunoblot on non-reduced brain or kidney microsomal preparations 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µL
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