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品种反应性 主要应用 宿主 格式 抗体类型 R, B, H, M WB, ICC M Purified Monoclonal Antibody 描述 产品目录编号 05-319 品牌系列 Upstate
商名 - Upstate
描述 Anti-Dynamin Antibody, Hudy 1 产品信息 格式 Purified 控制 - Brain tissue
演示 Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in PBS containing 0.2% gelatin and 0.05% sodium azide 应用 应用 Anti-Dynamin Antibody, Hudy 1 is an antibody against Dynamin for use in IC, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
生物信息 免疫原品种 Recombinant full length human Dynamin-1 表位 amino acids 822-838 克隆 Hudy 1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Recognizes an epitope (822-838) within the proline-rich domain of dynamin; also inhibits microtubule and grb2-stimulated dynamin GTPase activity. 同种型 IgG 品种反应性 RatBovineHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_004408
Entrez基因汇总 This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. 基因符号 - DNM
- DNM1
- dynamin
- dynamin1
- Dynamin-1
纯化方法 Protein G purfied UniProt编号 - Q05193
UniProt汇总 FUNCTION: SwissProt: Q05193 # Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.
SIZE: 864 amino acids; 97407 Da
SUBUNIT: Interacts with CAV1 and SH3GLB1. Binds SH3GL1, SH3GL2 and SH3GL3 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
SIMILARITY: SwissProt: Q05193 ## Belongs to the dynamin family. & Contains 1 GED domain. & Contains 1 PH domain.产品使用声明 质量保证 routinely evaluated in bovine brain cytosol or rat brain cytosol 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µg
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下一件merck millipore产品：merck millipore,默克密理博,12-219,Threonine Phosphopeptide (K-R-pT-I-R-R)
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