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merck millipore,默克密理博,05-175,Anti-Myb Antibody, clone 1-1
产品名称：Anti-Myb Antibody, clone 1-1
产品型号：05-175
Anti-Myb Antibody, clone 1-1 is a Mouse Monoclonal Antibody for detection of Myb also known as Avian myeloblastosis viral (v-myb) oncogene homolog 2 c-myb protein (140 AA) & has been validated in IHC, More>>
merck millipore,默克密理博,05-175,Anti-Myb Antibody, clone 1-1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB, IHC M Purified Monoclonal Antibody 描述 产品目录编号 05-175 品牌系列 Upstate
商名 - Upstate
描述 Anti-Myb Antibody, clone 1-1 Alternate Names - v-myb myeloblastosis viral oncogene homolog (avian)
- Avian myeloblastosis viral (v-myb) oncogene homolog 2 c-myb protein (140 AA)
- v-myb avian myeloblastosis viral oncogene homolog
- v-myb myeloblastosis viral oncogene homolog
背景信息 Myb is a transcriptional activator. It is a DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Myb plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. 产品信息 格式 Purified 控制 - Jurkat cell lysate.
Included Positive Antigen Control: Catalog # 12-303, Jurkat cell lysate. Add 2.5 μL of 2-mercaptoethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-glycine, pH 7.4, 0.15 M NaCl and 0.05% sodium azide. Frozen solution. 应用 应用 Anti-Myb Antibody, clone 1-1 is a Mouse Monoclonal Antibody for detection of Myb also known as Avian myeloblastosis viral (v-myb) oncogene homolog 2 c-myb protein (140 AA) & has been validated in IHC, IP & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunoprecipitation:
4 μg of previous lot immunoprecipitated Myb from Jurkat cell lysate.
Immunohistochemistry:生物信息 免疫原品种 Recombinant murine Myb purified by SDS-PAGE (Nicot, C., 2001) Clone 1-1. 克隆 1-1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes Myb, Mr 80 kDa, containing C-terminal amino acids from 401-636 (Salomoni, P., 1997). 同种型 IgG2aκ 品种反应性 MouseHuman Species Reactivity Note Human, Mouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_005375.2
基因符号 - c-myb10A_CDS
- MYB
- C-myb
- c-myb13A_CDS
- c-myb8B_CDS
- c-myb_CDS
- v-myb
- c-myb14A_CDS
- Cmyb
- c-myb
- efg
纯化方法 Ammonium sulfate precipitation, gel filtration, and ion-exchange chromatography. UniProt编号 - P10242
UniProt汇总 FUNCTION: SwissProt: P10242 # Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
SIZE: 640 amino acids; 72341 Da
SUBUNIT: Binds MYBBP1A. Interacts with HIPK2 and NLK (By similarity).
SUBCELLULAR LOCATION: Nucleus.
DOMAIN: SwissProt: P10242 Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C- terminal domain involved in transcriptional repression.
PTM: Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation (Probable). & Phosphorylated by NLK on multiple sites, which induces proteasomal degradation (By similarity).
SIMILARITY: Contains 3 HTH myb-type DNA-binding domains.产品使用声明 质量保证 Routinely evaluated on RIPA lysate from Jurkat cells.
Western Blot Analysis:
0.5-2 μg/mL of this lot detected Myb in 20 μg of RIPA lysate from Jurkat cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 250 µg
上一件merck millipore产品：merck millipore,默克密理博,401104,Human IgG, Fc Fragment, Plasma
下一件merck millipore产品：merck millipore,默克密理博,SF-740,E2F1; Human, Cyanine 3, RNA Detection Probe,SmartFlare
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