merck millipore,默克密理愽
  • merck millipore,默克密理博,04-039,Anti-20S proteasome subunit α2 Antibody, clone MCP21

  • merck millipore,默克密理博,04-039,Anti-20S proteasome subunit α2 Antibody, clone MCP21

    产品名称：Anti-20S proteasome subunit α2 Antibody, clone MCP21
    产品型号：04-039
    Anti-20S proteasome subunit α2 Antibody, clone MCP21 detects level of 20S proteasome subunit α2 & has been published & validated for use in IP, WB, IH.

    merck millipore,默克密理博,04-039,Anti-20S proteasome subunit α2 Antibody, clone MCP21

  • 产品介绍
  • merck millipore,默克密理博,04-039,Anti-20S proteasome subunit α2 Antibody, clone MCP21

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, B, HIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 04-039
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-20S proteasome subunit α2 Antibody, clone MCP21
    Alternate Names
    • HC3, proteasome subunit alpha type 2
    • HC3
    产品信息
    格式 Purified
    演示 100 µL concentration of 1mg/mL purified ascites in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
    应用
    应用 Anti-20S proteasome subunit α2 Antibody, clone MCP21 detects level of 20S proteasome subunit α2 & has been published & validated for use in IP, WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    生物信息
    免疫原品种 Human placenta derived proteasomes
    克隆 MCP21
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes proteasome subunit alpha type 2.
    同种型 IgG1
    品种反应性 RabbitBovineHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002787.3
    Entrez基因汇总 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
    基因符号
    • PMSA2
    • PSMA2
    • PSC3
    • MU
    • HC3
    • PSC2
    纯化方法 Ascites
    UniProt编号
    • P25787
    UniProt汇总 FUNCTION: SwissProt: P25787 # The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.
    SIZE: 234 amino acids; 25899 Da
    SUBUNIT: The proteasome is composed of at least 15 non identical subunits which form a highly ordered ring-shaped structure.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
    PTM: Phosphorylated on tyrosine residues; which may be important for nuclear import (By similarity).
    SIMILARITY: SwissProt: P25787 ## Belongs to the peptidase T1A family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of shipment for up to 12 months.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,04-039,Anti-20S proteasome subunit α2 Antibody, clone MCP21

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