merck millipore,默克密理愽
  • merck millipore,默克密理博,MAB1681,Anti-Vimentin Antibody, clone LN-6

  • merck millipore,默克密理博,MAB1681,Anti-Vimentin Antibody, clone LN-6

    产品名称：Anti-Vimentin Antibody, clone LN-6
    产品型号：MAB1681
    Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).

    merck millipore,默克密理博,MAB1681,Anti-Vimentin Antibody, clone LN-6

  • 产品介绍
  • merck millipore,默克密理博,MAB1681,Anti-Vimentin Antibody, clone LN-6

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HIH(P)MCulture SupernatantMonoclonal Antibody
    描述
    产品目录编号 MAB1681
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Vimentin Antibody, clone LN-6
    背景信息 Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
    产品信息
    格式 Culture Supernatant
    控制
    • Hyperplastic lymph nodes.
    演示 Liquid tissue culture supernatant.
    应用
    应用 Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
    主要应用
    • Immunohistochemistry (Paraffin)
    应用说明 Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
    生物信息
    免疫原品种 Nuclei from adult human thymic biopsy specimens.
    克隆 LN-6
    宿主 Mouse
    特异性 Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
    同种型 IgM
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_003380.2
    Entrez基因汇总 Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.[supplied by OMIM]
    基因符号
    • vimentin
    • VIM
    • FLJ36605
    • Vimentin.
    UniProt编号
    • P08670
    UniProt汇总 FUNCTION: SwissProt: P08670 # Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
    SIZE: 466 amino acids; 53652 Da
    SUBUNIT: Homopolymer. Component of a complex composed at least of ACTB, AP2M1, AP2A1, AP2A2, MEGF10 and VIM. Interacts with HCV core protein.
    TISSUE SPECIFICITY: Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines.
    PTM: One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.
    SIMILARITY: SwissProt: P08670 ## Belongs to the intermediate filament family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 1 mL

    merck millipore,默克密理博,MAB1681,Anti-Vimentin Antibody, clone LN-6

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