merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5585,Anti-Recoverin Antibody

  • merck millipore,默克密理博,AB5585,Anti-Recoverin Antibody

    产品名称：Anti-Recoverin Antibody
    产品型号：AB5585
    Detect Recoverin using this Anti-Recoverin Antibody validated for use in IC, IH, IH(P) & WB.

    merck millipore,默克密理博,AB5585,Anti-Recoverin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5585,Anti-Recoverin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Fg, H, M, R, ChWB, ICC, IHCRbSerumPolyclonal Antibody
    描述
    产品目录编号 AB5585
    Replaces AB5431P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Recoverin Antibody
    Alternate Names
    • Recoverin
    背景信息 Recoverin is a calcium-binding protein expressed in retinal photoreceptors and midget cone bipolar cells. It appears to delay the termination of the phototransduction cascade by blocking the phosphorylation of photoexcited rhodopsin.
    产品信息
    格式 Serum
    控制
    • POSITIVE CONTROL: Recoverin is found in photoreceptors and midget cone bipolar cells in retina and pinealocytes in pineal gland.
    演示 Rabbit polyclonal serum. Contains no preservative.
    应用
    应用 Detect Recoverin using this Anti-Recoverin Antibody validated for use in IC, IH, IH(P) & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Western Blot Analysis:
    1:1,000-1:5,000 dilution using ECL.

    Immunohistochemistry:
    1:1,000 (2 hours at room temperature or overnight at 2-8ºC) on frozen and paraffin embedded tissue sections. Suggested fixative is 4% paraformaldehyde or 3% paraformaldehyde with 0.1% glutaraldehyde. Suggested permeabilization solution is 0.1% Triton X-100. Suggested blocking buffer is 0.05 M Tris saline, pH 7.4 containing 2.5% BSA, 0.1% triton and 0.05% sodium azide.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Recombinant human recoverin.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes recoverin.
    品种反应性 FrogHumanMouseRatChicken
    Species Reactivity Note Human, rat, mouse, chicken and frog. Other species have not been tested.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002903.2
    Entrez基因汇总 This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
    基因符号
    • RCV1
    • RCVRN
    • Recoverin
    纯化方法 Unpurified
    UniProt编号
    • P35243
    UniProt汇总 FUNCTION: SwissProt: P35243 # Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.
    SIZE: 200 amino acids; 23130 Da
    TISSUE SPECIFICITY: Retina and pineal gland.
    DISEASE: SwissProt: P35243 # Identified as the antigen in cancer-associated retinopathy, an autoimmune disease of the retina caused by a tumor in another tissue.
    SIMILARITY: SwissProt: P35243 ## Belongs to the recoverin family. & Contains 4 EF-hand domains.
    MISCELLANEOUS: Binds two calcium ions; one with high affinity, the other with low affinity.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20ºC from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5585,Anti-Recoverin Antibody

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