merck millipore,默克密理愽
  • merck millipore,默克密理博,481411,NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem

  • merck millipore,默克密理博,481411,NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem

    产品名称：NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem
    产品型号：481411
    The NF-κB Activation Inhibitor III, also referenced under CAS 380623-76-7, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applic More>>

    merck millipore,默克密理博,481411,NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,481411,NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₅ClN₄O₅S380623-76-7
    描述
    概述 A cell-permeable thiazoloamide compound that inhibits TNF-α-stimulated NF-κB activation and subsequent upregulation of MMP-9 in HT1080 cells (complete inhibition at 10 µM). The inhibition of MMP-9 upregulation correlates with a concomitant inhibition of TNF-α-dependent cell invasion. Does not affect TNF-α-induced AP-1 activity. The cellular target appears to be downstream of p38 activation.
    产品目录编号 481411
    品牌系列 Calbiochem®
    同义词 3-Chloro-4-nitro-N-(5-nitro-2-thiazolyl)-benzamide, SM-7368
    参考
    参考 Lee, H.Y., et al. 2005. Biochem. Biophys. Res. Commun. 336, 716.
    产品信息
    CAS号 380623-76-7
    具有ATP竞争性 N
    形式 Light yellow amorphous solid
    Hill配方 C₁₀H₅ClN₄O₅S
    化学配方 C₁₀H₅ClN₄O₅S
    Molar Mass 328.7
    可逆 N
    结构配方图像
    生物信息
    主靶 TNF-α-stimulated NF-κB activation and upregulation of MMP-9
    主靶IC50 Effective concentration: 10 µM for complete inhibition of TNF-α-stimulated NF-κB activation and subsequent upregulation of MMP-9 in HT1080 cells
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,481411,NF-κB Activation Inhibitor III - CAS 380623-76-7 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,MABS146,Anti-RasGRP1 Antibody, clone 10.1
下一件merck millipore产品：merck millipore,默克密理博,565790,γ-Secretase Inhibitor XXI, Compound E - CAS 209986-17-4 - Calbiochem


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