merck millipore,默克密理愽
  • merck millipore,默克密理博,MABE157,Anti-HOXD4 Antibody, clone 8E11.1

  • merck millipore,默克密理博,MABE157,Anti-HOXD4 Antibody, clone 8E11.1

    产品名称：Anti-HOXD4 Antibody, clone 8E11.1
    产品型号：MABE157
    Anti-HOXD4 Antibody, clone 8E11.1 is a Mouse Monoclonal Antibody for detection of HOXD4 also known as Homeobox protein Hox-D4 & has been validated in WB.

    merck millipore,默克密理博,MABE157,Anti-HOXD4 Antibody, clone 8E11.1

  • 产品介绍
  • merck millipore,默克密理博,MABE157,Anti-HOXD4 Antibody, clone 8E11.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, RWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABE157
    描述 Anti-HOXD4 Antibody, clone 8E11.1
    Alternate Names
    • Homeobox protein Hox-5.1
    • Homeobox protein Hox-D4
    • Homeobox protein HHO.C13
    • Homeobox protein Hox-4B
    背景信息 This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. It is reported that all Hox paralog group 4 members, A4, B4, C4, and D4, have similar effects on hematopoietic stem and progenitor self-renewal in vitro. It is shown that each paralog group 4 member both promotes proliferation and inhibits differentiation, thereby enabling the exponential expansion of hematopoietic progenitors from c-kit(+)/CD41(+) cell fractions of day 6 murine embryoid bodies.
    产品信息
    格式 Purified
    控制
    • Rat kidney tissue lysate
    演示 Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
    应用
    应用 Anti-HOXD4 Antibody, clone 8E11.1 is a Mouse Monoclonal Antibody for detection of HOXD4 also known as Homeobox protein Hox-D4 & has been validated in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human HOXD4.
    克隆 8E11.1
    宿主 Mouse
    同种型 IgMκ
    品种反应性 MouseRat
    Species Reactivity Note Demonstrated to react with Rat and Mouse. Predicted to react with Human based on immunogen design.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_055436
    Entrez基因汇总 This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.
    基因符号
    • HOX4B
    • HOXD4
    纯化方法 Purified by ion exchange chromatography
    UniProt编号
    • P09016
    UniProt汇总 FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

    SUBCELLULAR LOCATION: Nucleus.
    产品使用声明
    质量保证 Evaluated by Western Blot in rat kidney tissue lysate.

    Western Blot Analysis: A 1:1,2000 dilution of this antibody detected HOXD4 in 10 µg of rat kidney tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABE157,Anti-HOXD4 Antibody, clone 8E11.1

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