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merck millipore,默克密理博,MABC684,Anti-SOD1 Antibody, clone 6F5
产品名称：Anti-SOD1 Antibody, clone 6F5
产品型号：MABC684
Anti-SOD1 Antibody, clone 6F5 is a highly specific mouse monoclonal antibody, that targets Superoxide Dismutase & has been tested in western blotting, ICC & Flow Cytometry.
merck millipore,默克密理博,MABC684,Anti-SOD1 Antibody, clone 6F5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H FC, WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 MABC684 描述 Anti-SOD1 Antibody, clone 6F5 Alternate Names - hSod1
- ALS
- SOD
- ALS1
- IPOA
- homodimerSuperoxide dismutase [Cu-Zn]
- Superoxide dismutase 1
背景信息 Superoxide dismutase 1 (SOD1) also known as Superoxide dismutase [Cu-Zn] to distinguish it from SOD2 which uses manganese as its cofactor, is the cytosolic form of the enzyme that catalyzes the breakdown of superoxide into oxygen and hydrogen peroxide and is our primary anti-oxidant combating enzyme. SOD1 performs its function with the help of co-factors and one protein in particular is vital to its proper functioning. Copper chaperone protein (CCS) is a metalloprotein that specifically delivers Cu to SOD1 and may activate SOD1 through direct insertion of the Cu cofactor. Interestingly, defects in SOD1 are the cause of a form of ALS (Amyotrophic Lateral Sclerosis or Lou Gehrig's disease) and much research is centered on understanding how over-active or under-active SOD1 contributes to the disease. EMD-Millipore's Anti-SOD1 mouse monoclonal antibody has been tested in western blot on HeLa, NIH3T3, A549 and A431 cell lysates and fluorescent immunocytochemistry on PANC1, SKBR-3 and 3T3-L1 cells in culture. The antibody has also been tested in flow cytometry on A431 cells in culture. 产品信息 格式 Ascites 控制 - HeLa, NIH/3T3, A549, and A431 cell lysates
演示 Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide. 应用 应用 Anti-SOD1 Antibody, clone 6F5 is a highly specific mouse monoclonal antibody, that targets Superoxide Dismutase & has been tested in western blotting, ICC & Flow Cytometry. 主要应用 - Flow Cytometry
- Western Blotting
- Immunocytochemistry
应用说明 Immunocytochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected SOD1 in PANC-1, SKBR-3, and 3T3-L1 cells.
Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected SOD1 in non serum starved A431 cells.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Purified recombinant fragment of human SOD1 expressed in E. Coli. 克隆 6F5 宿主 Mouse 同种型 IgG1 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody 基因符号 - SOD1
纯化方法 Unpurified UniProt编号 - P00441
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa, NIH/3T3, A549, and A431 cell lysates.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected SOD1 in HeLa, NIH/3T3, A549, and A431 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.包装信息 数量 100 µL
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