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merck millipore,默克密理博,FCMAB318PE,Milli-Mark™ Anti-MAP2-PE Antibody, clone AP20
产品名称:Milli-Mark™ Anti-MAP2-PE Antibody, clone AP20
产品型号:FCMAB318PE
Milli-Mark Anti-MAP2-PE Antibody, clone AP20 is an antibody against MAP2 for use in FC.
merck millipore,默克密理博,FCMAB318PE,Milli-Mark™ Anti-MAP2-PE Antibody, clone AP20
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC M Phycoerythrin Monoclonal Antibody 描述 产品目录编号 FCMAB318PE 商名 - Milli-Mark
描述 Milli-Mark™ Anti-MAP2-PE Antibody, clone AP20 Alternate Names - Microtubule-associated protein 2
背景信息 MAP-2 (microtubule associated protein-2) is one of several high molecular weight proteins that play an important role in brain neuron microtubule assembly. In addition to its association with microtubules, MAP-2 associates with neurofilaments and actin filaments suggesting that it may guide interaction among microtubules, other cytoskeletal elements, and cytoplasmic organelles. MAP-2 is a stringent marker for neurons. In addition, MAP-2 displays intracellular specificity. In the central nervous system, MAP-2 is confined to neuronal cell bodies and dendrites. There are exceptions, however, where some axons stain positive for small amounts of MAP-2. MAP-2 is uniformly distributed throughout the cell when first expressed in cultured neurons but becomes selectively localized as dendritic development proceeds. (Caceres, 1986; Dotti, 1987). 产品信息 格式 Phycoerythrin 控制 - U251 cells
演示 Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Milli-Mark Anti-MAP2-PE Antibody, clone AP20 is an antibody against MAP2 for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Recombinant Bovine brain microtubule protein. 克隆 AP20 宿主 Mouse 特异性 Antibody recognizes MAP-2. 同种型 IgG1 品种反应性 Human Species Reactivity Note Tested and passed on Human. Predicted to react on Bovine based on immunogen designed. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002365
Entrez基因汇总 This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described. 基因符号 - MAP2
纯化方法 Protein A Purified UniProt编号 - P11137
UniProt汇总 FUNCTION: SwissProt: P11137 # The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
SIZE: 1827 amino acids; 199539 Da
PTM: MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P11137 ## Contains 3 Tau/MAP repeats.产品使用声明 质量保证 Evaluated by flow cytometry using U251 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt. 包装信息 数量 100 tests
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