merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5725,Anti-Gephyrin Antibody

  • merck millipore,默克密理博,AB5725,Anti-Gephyrin Antibody

    产品名称：Anti-Gephyrin Antibody
    产品型号：AB5725
    Anti-Gephyrin Antibody is an antibody against Gephyrin for use in WB.

    merck millipore,默克密理博,AB5725,Anti-Gephyrin Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5725,Anti-Gephyrin Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5725
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Gephyrin Antibody
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid.
    应用
    应用 Anti-Gephyrin Antibody is an antibody against Gephyrin for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 0.5-1.0 μg/mL using ECL on mouse cerebellum tissue lysate. The antibody reacts with a protein of ~93 kDa. An additional band of ~35 kDa may also be seen depending on sample used.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide from rat gephyrin.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Gephyrin
    品种反应性 RatMouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_020806.4
    • NM_001024218.1
    Entrez基因汇总 This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known.
    基因符号
    • KIAA1385
    • GPHN
    • GPHRYN
    • GPH
    • gephyrin
    • GEPH
    • Gephyrin.
    UniProt编号
    • Q9NQX3
    UniProt汇总 FUNCTION: SwissProt: Q9NQX3 # Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Involved in molybdenum cofactor biosynthesis. Required for molybdenum transfer to molybdopterin. In a first step, copper-molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released (By similarity).
    COFACTOR: Magnesium (By similarity).
    SIZE: 736 amino acids; 79748 Da
    SUBUNIT: Homotrimer. Interacts with GABARAP (By similarity).
    DOMAIN:SwissProt: Q9NQX3 Contains 2 functional domains that are expressed as separate proteins in bacteria. The G-domain adenylates molybdopterin. The E-domain inserts molybdenum into adenylated molybdopterin.
    DISEASE: SwissProt: Q9NQX3 # Defects in GPHN are the cause of molybdenum cofactor deficiency type C (MOCOD type C) [MIM:252150]. MOCOD type C is an autosomal recessive disease which leads to the pleiotropic loss of all molybdoenzyme activities and is characterized by severe neurological damage, neonatal seizures and early childhood death.
    SIMILARITY: In the N-terminal section; belongs to the moaB/mog family. & In the C-terminal section; belongs to the moeA family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at +2-8°C in undiluted aliquots for up to 6 months after date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB5725,Anti-Gephyrin Antibody

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