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品种反应性 主要应用 宿主 格式 抗体类型 R, M WB, ELISA Ch Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB3521 Replaces MAB3870 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Leptin Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide. 应用 应用 Detect Leptin using this Anti-Leptin Antibody validated for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
应用说明 Immunoblotting: 1:1,000-1:5,000
ELISA: 1:1,000-1:5,000
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Recombinant rat leptin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Chicken 特异性 Leptin, rat and mouse. 品种反应性 RatMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000230.1
Entrez基因汇总 This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. 基因符号 - OBS
- LEP
- leptin
- OB
- obesity
UniProt编号 - P41159
UniProt汇总 FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
SIZE: 167 amino acids; 18641 Da
SUBUNIT: Interacts with SIGLEC6.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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