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描述 产品目录编号 9011S 描述 Human Specific–Ultra Sensitive Insulin 背景信息 These iodinated hormonos are HPLC purified and prepared fresh monthly. 产品信息 格式 Iodinated Hormones 应用 应用说明 appropriate label hydrating buffer if kit replacement or assay buffer of choice 生物信息 Entrez基因编号 - NM_000207.2
Entrez基因汇总 After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. 基因符号 - insulin
- INS
- proinsulin
标签 125Iodine UniProt编号 - P01308
UniProt汇总 FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.理化信息 放射性 <3 μCi 储存和货运信息 存储条件 2–8 °C 包装信息 数量 250 tubes
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