merck millipore,默克密理博,855015,Amino PEGA resin

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merck millipore,默克密理博,855015,Amino PEGA resin
产品名称：Amino PEGA resin
产品型号：855015
Novabiochem

merck millipore,默克密理博,855015,Amino PEGA resin

产品介绍

merck millipore,默克密理博,855015,Amino PEGA resin

重要规格表

CAS号
372109-59-6

描述
概述	"PEGA resins consist of dimethyl acrylamide and mono-2-acrylamidoprop-1-yl[2-aminoprop-1-yl] polyethylene glycol cross-linked with bis 2-acrylamidoprop-1-yl polyethyleneglycol. These supports swell extensively in a wide range of solvents and are permeable to macromolecules up to 35 kD, making them ideal for the preparation of combinatorial libraries, affinity purification and on-resin enzyme assays. For applications of these resins in SPPS and SPOS see [1-18].Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail. The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus. The product number for this product was previously 01-64-0100. To obtain a certificate of analysis (CoA) of a lot that begins with the letter ""A"", please select the option in the right hand menu ""Request a COA for Lot#s starting with A""
产品目录编号	855015
品牌系列	Novabiochem®
同义词	01-64-0100

参考
参考	"[1] M. Meldal, et al. (1992) Tetrahedron Lett., 33, 3077. [1] M. Meldal, et al. (1992) Tetrahedron Lett., 33, 3077. [2] F. I. Auzanneau, et al. (1994) J. Peptide Sci., 1, 31. [3] M. Meldal in "Peptides 1992, Proc. 22nd European Peptide Symposium", C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 61. [4] M. Meldal, et al. in "Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium", R. Epton (Eds), Mayflower Worldwide, Birmingham, 1994, pp. 259. [5] M. Meldal, et al. (1993) Int. J. Peptide Protein Res., 41, 250. [6] M. Meldal, et al. (1994) J. Chem. Soc., Chem. Commun., 1849. [7] M. Meldal, et al. (1994) Proc. Natl. Acad. Sci. USA, 91, 3314. [8] M. Renil, et al. (1998) J. Peptide Sci., 4, 195. [9] J. C. Spetzler, et al. (1998) J. Peptide Sci., 4, 128. [10] M. Meldal, et al. (1998) J. Peptide Sci., 4, 83. [11] J. A. Camarero, et al. (1998) J. Peptide Res., 51, 303. [12] J. A. Camarero, et al. (2000) Lett. Pept. Sci., 7, 17. [13] O. Melnyk, et al. (2001) J. Org. Chem., 66, 4153. [14] J. Buchardt, et al. (2000) J. Comb. Chem., 2, 624. [15] J. F. Tolberg, et al. (2002) J. Org. Chem., 67, 4143. [16] J. Bondebjerg, et al. (2002) J. Am. Chem. Soc., 124, 11046. [17] J. Tulla-Puche, et al. (2004) J. Org. Chem., 69, 4101. [18] S. Aggarwal, et al. (2005) Biomaterials, 26, 6077."

参考

"[1] M. Meldal, et al. (1992) Tetrahedron Lett., 33, 3077.
[1] M. Meldal, et al. (1992) Tetrahedron Lett., 33, 3077.
[2] F. I. Auzanneau, et al. (1994) J. Peptide Sci., 1, 31.
[3] M. Meldal in "Peptides 1992, Proc. 22nd European Peptide Symposium", C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 61.
[4] M. Meldal, et al. in "Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium", R. Epton (Eds), Mayflower Worldwide, Birmingham, 1994, pp. 259.
[5] M. Meldal, et al. (1993) Int. J. Peptide Protein Res., 41, 250.
[6] M. Meldal, et al. (1994) J. Chem. Soc., Chem. Commun., 1849.
[7] M. Meldal, et al. (1994) Proc. Natl. Acad. Sci. USA, 91, 3314.
[8] M. Renil, et al. (1998) J. Peptide Sci., 4, 195.
[9] J. C. Spetzler, et al. (1998) J. Peptide Sci., 4, 128.
[10] M. Meldal, et al. (1998) J. Peptide Sci., 4, 83.
[11] J. A. Camarero, et al. (1998) J. Peptide Res., 51, 303.
[12] J. A. Camarero, et al. (2000) Lett. Pept. Sci., 7, 17.
[13] O. Melnyk, et al. (2001) J. Org. Chem., 66, 4153.
[14] J. Buchardt, et al. (2000) J. Comb. Chem., 2, 624.
[15] J. F. Tolberg, et al. (2002) J. Org. Chem., 67, 4143.
[16] J. Bondebjerg, et al. (2002) J. Am. Chem. Soc., 124, 11046.
[17] J. Tulla-Puche, et al. (2004) J. Org. Chem., 69, 4101.
[18] S. Aggarwal, et al. (2005) Biomaterials, 26, 6077."

产品信息
CAS号	372109-59-6
HS代码	3907 20 99
结构配方图像

GHS安全信息
储存类别	10 - 13 其它液体及固体
WGK	WGK 1 轻度的水危害

储存和货运信息
储存	于 +2°C 到 +8°C储存.

规格
规格
Colour (visual)	white to yellow to beige
Appearance of substance (visual)	beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)	0,30 - 0,50 mmol/g
Swelling Volume (in DMF)	lot specific result
Swelling Volume (in water)	lot specific result
dry resin %	lot specific result
The resin is sold swollen in ethanol. 50 - 100 mesh

merck millipore,默克密理博,855015,Amino PEGA resin

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