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CAS号 Hill配方 摩尔质量 378247-75-7 C₂₆H₁₉NO₆ 441.43 g/mol 描述 概述 Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide. 产品目录编号 852309 品牌系列 Novabiochem®
参考 参考 [1] J. L. Harris, et al. (2000) Proc. Natl. Acad. Sci. USA, 97, 7754.
[2] D. J. Maly, et al. (2002) J. Org. Chem., 67, 910.
[3] C. M. Salisbury, et al. (2002) J. Am. Chem. Soc., 124, 14868.产品信息 CAS号 378247-75-7 Hill配方 C₂₆H₁₉NO₆ Molar Mass 441.43 g/mol HS代码 2932 20 90 GHS安全信息 储存类别 10 - 13 其它液体及固体 WGK WGK 2 水危害 一次性 3
反应性相对较低的有机物必须被收集在第A类, 如果被卤化则在第B类, 如果为固体残留物则归在第C类.储存和货运信息 储存 于 +2°C 到 +8°C储存. 规格 规格 Colour (visual) white to slight yellow to light red Appearance of substance (visual) powder Identity (IR) conforms Purity (TLC(CMA1)) ≥ 98 %(m) Assay (HPLC, area%) ≥ 95,0 Area % Solubility (1 mmole in 2 ml DMF) clearly soluble For TLC-Systems see our General Catalog
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