• merck millipore,默克密理博,852046,Fmoc-Ser(Trt)-OH
  • merck millipore,默克密理博,852046,Fmoc-Ser(Trt)-OH

    产品名称:Fmoc-Ser(Trt)-OH
    产品型号:852046
    Novabiochem

    merck millipore,默克密理博,852046,Fmoc-Ser(Trt)-OH

  • 产品介绍
  • merck millipore,默克密理博,852046,Fmoc-Ser(Trt)-OH

    重要规格表

    CAS号 Hill配方 摩尔质量
    111061-56-4C₃₇H₃₁NO₅569.65 g/mol
    描述
    概述 "The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS [1, 2] or 20% dichloroacetic acid in DCM [3], enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphoserine containing peptides and peptides modified at the serine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2, 4].
    The product number for this product was previously 04-12-1092.
    To obtain a certificate of analysis (CoA) of a lot that begins with the letter ""A"", please select the option in the right hand menu ""Request a COA for Lot#s starting with A""
    产品目录编号 852046
    品牌系列 Novabiochem®
    同义词 04-12-1092;"N-α-Fmoc-O-trityl-L-serine
    参考
    参考 "[1] K. Barlos, et al. (1991) Tetrahedron Lett., 32, 471.
    [2] K. Barlos, et al. (1998) J. Peptide Res., 51, 194.
    [3] M. P. Coba, et al. (2003) J. Peptide Res., 61, 17.
    [4] X.-H. Tong, et al. in "Peptide Revolution: Genomics, Proteomics & Therapeutics, , Proc. 18th American Peptide Symposium", M. Chrev & T. K. Sawyer (Eds), Cardiff, American Peptide Society, 2003, pp. 21."
    产品信息
    CAS号 111061-56-4
    Hill配方 C₃₇H₃₁NO₅
    Molar Mass 569.65 g/mol
    HS代码 2924 29 98
    结构配方图像
    理化信息
    熔点 200 °C
    GHS安全信息
    储存类别 10 - 13 其它液体及固体
    WGK WGK 2 水危害
    储存和货运信息
    储存 "-20 °C
    规格
    规格
    Colour (visual)white to slight yellow to beige
    Appearance of substance (visual)powder
    Identity (IR)passes test
    Purity (TLC(011A))≥ 98 %
    Purity (TLC(0811))≥ 98 %
    Enantiomeric purity≥ 99.5 % (a/a)
    Assay (HPLC, area%)≥ 98.0 % (a/a)
    Solubility (1 mmole in 2 ml DMF)clearly soluble
    Assay (acidimetric)≥ 95.0 %
    Water (K. F.)≤ 2.0 %
    For TLC-Systems see our General Catalog

    merck millipore,默克密理博,852046,Fmoc-Ser(Trt)-OH

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