• merck millipore,默克密理博,400086,HIF Inhibitor VI - Calbiochem
  • merck millipore,默克密理博,400086,HIF Inhibitor VI - Calbiochem

    产品名称:HIF Inhibitor VI - Calbiochem
    产品型号:400086
    The HIF-1 Inhibitor, NSC-134754 controls the biological activity of HIF-1. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,400086,HIF Inhibitor VI - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,400086,HIF Inhibitor VI - Calbiochem

    重要规格表

    经验配方
    C₂₇H₃₄N₂O₂
    描述
    概述 A cell-permeable emetan derivative that selectively reduces HIF-1 activity by 73% in a luciferase reporter assay, and blocks HIF-1α protein induction in response to DFX, hypoxia, and IGF-1 in U2OS-HRE-luc cells at 10 µM, without significantly inhibiting cell growth. Furthermore, it is shown to completely block HIF-1α induced by IGF-1 in HCT116 human colon carcinoma cells.
    产品目录编号 400086
    品牌系列 Calbiochem®
    同义词 NSC-134754
    参考
    参考 Chau, N.M., et al. 2005. Cancer Res. 65, 4918.
    产品信息
    形式 Brown solid
    Hill配方 C₂₇H₃₄N₂O₂
    化学配方 C₂₇H₃₄N₂O₂
    Molar Mass 418.6
    结构配方图像
    生物信息
    纯度 ≥90% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,400086,HIF Inhibitor VI - Calbiochem

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