merck millipore,默克密理愽
  • merck millipore,默克密理博,200499,Bexarotene - CAS 153559-49-0 - Calbiochem

  • merck millipore,默克密理博,200499,Bexarotene - CAS 153559-49-0 - Calbiochem

    产品名称：Bexarotene - CAS 153559-49-0 - Calbiochem
    产品型号：200499
    A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-dependent manner.

    merck millipore,默克密理博,200499,Bexarotene - CAS 153559-49-0 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,200499,Bexarotene - CAS 153559-49-0 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₄H₂₈O₂153559-49-0
    描述
    概述 A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6 h and 50% reduction in 72 h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of Aβ proteases, insulin degrading enzyme, and neprilysin.
    产品目录编号 200499
    品牌系列 Calbiochem®
    同义词 4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid
    参考
    参考 Cramer, P.E., et al. 2012. Science Exp. 335, 1503.
    产品信息
    CAS号 153559-49-0
    形式 White powder
    Hill配方 C₂₄H₂₈O₂
    化学配方 C₂₄H₂₈O₂
    Molar Mass 348.5
    可逆 Y
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Regulatory Review
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,200499,Bexarotene - CAS 153559-49-0 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,535142,Protease Inhibitor Cocktail Set I, Animal-Free - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,AB947-K,Anti-Apolipoprotein E (1L)


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