merck millipore,默克密理愽
  • merck millipore,默克密理博,121765,AG 825 - CAS 149092-50-2 - Calbiochem

  • merck millipore,默克密理博,121765,AG 825 - CAS 149092-50-2 - Calbiochem

    产品名称：AG 825 - CAS 149092-50-2 - Calbiochem
    产品型号：121765
    A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC₅₀ = 0.35 µM) relative to HER1 (IC₅₀= 19 µM) autophosphorylation.

    merck millipore,默克密理博,121765,AG 825 - CAS 149092-50-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,121765,AG 825 - CAS 149092-50-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₅N₃O₃S₂149092-50-2
    描述
    概述 A potent, cell-premeable, reversible, substrate competitive, and selective inhibitor of HER2 (neu/ErbB2; IC50 = 0.35 µM) relative to HER1 (IC50 = 19 µM) autophosphorylation. The inhibition is competitive with respect to ATP binding. Enhances chemosensitivity in non-small cell lung cancer (NSCLC) cell lines expressing high levels of p185neu.
    产品目录编号 121765
    品牌系列 Calbiochem®
    同义词 4-Hydroxy-3-methoxy-5-(benzothiazolylthiomethyl)benzylidenecyanoacetamide
    参考
    参考 Ashton, J.M., et al. 2012. Cell Stem Cell 11, 359.
    Tsai, C.M., et al. 1996. Cancer Res. 56, 1068.
    Levitzki, A., and Gazit, A. 1995. Science 267, 1782.
    Osherov, N., et al. 1993. J. Biol. Chem. 268, 11134.
    产品信息
    CAS号 149092-50-2
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₉H₁₅N₃O₃S₂
    化学配方 C₁₉H₁₅N₃O₃S₂
    Molar Mass 397.5
    可逆 Y
    结构配方图像
    生物信息
    主靶 HER2
    主靶IC50 0.35 µM against HER2
    纯度 ≥94% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2-3 months at -20°C.

    merck millipore,默克密理博,121765,AG 825 - CAS 149092-50-2 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,CBL180P,Anti-E-Selectin Antibody, clone 1.2B6, Phycoerythrin conjugated
下一件merck millipore产品：merck millipore,默克密理博,20-210,Catch and Release Wash Buffer, 10X


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