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品种反应性 主要应用 宿主 格式 抗体类型 Mk, H WB, EMSA M Purified Monoclonal Antibody 描述 产品目录编号 05-563 Replaces CBL447 品牌系列 Upstate
商名 - Upstate
描述 Anti-RBP1 Antibody, clone LY11 产品信息 格式 Purified 演示 PBS and 0.03% thimerosol before the addition of glycerol to 30% 应用 应用 Detect RBP1 with Anti-RBP1 Antibody, clone LY11 (Mouse Monoclonal Antibody), that has been shown to work in EMSA, IP & WB. 主要应用 - Western Blotting
- Electrophoretic Mobility Shift Assay
生物信息 免疫原品种 GST fusion-protein corresponding to residues 154-679 of human RBP1. 克隆 clone LY11 宿主 Mouse 特异性 RBP1 同种型 IgG 品种反应性 MonkeyHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002892
Entrez基因汇总 Key regulator of entry into cell division that acts as a tumor suppressor. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting chromatin-modifying enzymes to promoters. Inhibits the intrinsic kinase activity of TAF1. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. 基因符号 - Retinoblastoma-associated protein
- RBP1
- PP110
- OSRC
- P105-RB
- retinoblastoma-1
- retinoblastoma suspectibility protein
纯化方法 Protein A chromatography UniProt编号 - P06400
UniProt汇总 Size: 928 amino acids; 106159 Da
Subunit: Interacts preferentially with transcription factor E2F1. The unphosphorylated form iinteracts with ARID3B, JARID1A, SUV39H1, MJD2A/JHDM3A and THOC1.
Interacts with the N-terminal domain of TAF1. Interacts with AATF, DNMT1, LIN9, LMNA, SUV420H1, SUV420H2, PELP1 and TMPO-alpha.
May interact with KNTC2. Interacts with EID1 and ZUBR1. Interacts with ARID4A and JARID1B
Subcellular location: Nucleus产品使用声明 质量保证 routinely evaluated by immunoblot on Jurkat nuclear extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,ABE30,Anti-RNA polymerase II subunit B1 Antibody, clone 4F8
下一件merck millipore产品：merck millipore,默克密理博,NA26,Anti-MSH2 (Ab-1) Mouse mAb (GB12)
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